Simulating the Efflux Models of Chloroquine in the Plasmodium Falciparum Resistance (PfCRT) Mechanism.

Simulating the Efflux Models of Chloroquine in the Plasmodium Falciparum Resistance (PfCRT) Mechanism.

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Chloroquine (CQ), cheap and long history antimalaria has failed in the treatment of malaria. This work sought to simulate the CQ efflux models of the resistance mechanism(s) of the human malaria parasite, Pf to CQ in the acidic food vacuole of the parasite. Following the introduction of Chloroquine as a first-line antimalaria and most widely used drug for the treatment of malaria, it is also...
 
Published at Proceedings of the second joint meeting of ISCB and ASBCB and the third conference of the ASBCB on Bioinformatics of African Pathogens, Hosts and Vectors. Cape Town, South Africa from 5 – 11 March 2011.
Published in 2011
 
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Adebiyi, O. Marion
Olumarion
 
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