Simulating the Efflux Models of Chloroquine in the Plasmodium Falciparum Resistance (PfCRT) Mechanism.

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Chloroquine (CQ), cheap and long history antimalaria has failed in the treatment of malaria. This work sought to simulate the CQ efflux models of the resistance mechanism(s) of the human malaria parasite, Pf to CQ in the acidic food vacuole of the parasite. Following the introduction of Chloroquine as a first-line antimalaria and most widely used drug for the treatment of malaria, it is also...

Published at Proceedings of the second joint meeting of ISCB and ASBCB and the third conference of the ASBCB on Bioinformatics of African Pathogens, Hosts and Vectors. Cape Town, South Africa from 5 – 11 March 2011.

Published in 2011

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Adebiyi, O. Marion

ADEBIYI MARION » Marion is cautious, self motivated and goal oriented. She is interested in Bioinformatics, anti-malaria drugs resistance mechanism, insecticide resistance mechanism and in-silico analysis of organism’s inter-pathways using the microarray and NGS data. She is the West African RSG president, African Society of Bioinformatics and Computational Biology (ASBCB) since 2008. view full profile